AFFiRiS is a clinical-stage biopharmaceutical company that pursues the ultimate aim to improve the lives of patients suffering from neurodegenerative diseases by providing disease-modifying specific active immunotherapies (SAIT) based on its proprietary patented AFFITOME® technology.
We strive to deliver much‑needed therapies to patients with debilitating and life‑threatening neurodegenerative diseases, such as Parkinson’s disease, multiple system atrophy (MSA), dementia with Lewy Bodies (DLB), and Huntington’s disease.
We aim to surpass currently available treatments.
RECENT PRESS RELEASES
18 June 2020
The Lancet Neurology publishes positive results of AFFiRiS’ Phase 1 trial with PD01A in Parkinson’s disease patients
9 April 2020
World Parkinson’s Day: AFFiRiS developing PD01 to treat Parkinson’s disease, a major unmet medical need
3 June 2020
Neurobiology of Disease publishes encouraging preclinical results of AFFiRiS’ antibody mAB C6-17 to treat Huntington’s disease
WHERE TO MEET US
28 January 2020
Biomed Event by Invest Securities
Paris, France
23-25 March 2020
Bio-Europe Spring
Paris, France
11-12 May 2020
The Neuro4D Conference 2020
Mainz, Germany
We focus on unmet medical needs in neurodegenerative diseases
Neurodegenerative diseases can have devastating effects on the quality of life of patients and family members, and often worsen over time. Currently available treatments for many of these diseases aim to manage symptoms, and do not stop or reverse progression. As a result, neurodegenerative diseases often lead to a progressively reduced quality of life. Therefore, better treatments for neurodegenerative diseases are needed to give patients healthier, happier, and longer lives.
We embrace this opportunity.
Specific Active ImmunoTherapy (SAIT)
Adherence to current therapies can be poor due to complex dosing regimens, and the treatment of many neurodegenerative diseases is stillinadequate. Using our unique AFFITOME technology, we are developing Specific Active ImmunoTherapy (SAIT), which stimulates the body to find and fight proteins central to the development and progression of neurodegenerative diseases. SAIT induces a long‑lasting target-specific immune response, which may be generated by far less frequent dosing regimens (e.g. once or twice a year)
SAIT is an exciting prospect.
Our pipeline
We focus on identifying proteins that are involved in the development and progression of neurodegenerative diseases, and establishing novel SAIT treatments against pathogenic forms of these proteins using our unique AFFITOME technology. SAIT has successfully demonstrated proof of concept in both preclinical and clinical studies. Our most advanced product candidates are entering Phase II clinical trials.
We are moving forward.
Collaborators
We intensively collaborate with a range of companies, universities, and foundations during the development of our novel SAIT treatments.
Be part of our journey.
Investors
We have a broad portfolio of immunotherapies that can be used in the treatment of a variety of neurodegenerative diseases, supported by a range of companies.
Partner with us.
Contact us
AFFiRiS AG
Karl-Farkas-Gasse 22
1030 Vienna, Austria
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+43 (1) 798 15 75 – 300
+43 (1) 798 15 75 – 311
office@affiris.com
